PH23357A - Cyclosporin compound,pharmaceutical composition containing said compound and method of use thereof - Google Patents

Cyclosporin compound,pharmaceutical composition containing said compound and method of use thereof

Info

Publication number
PH23357A
PH23357A PH32014A PH32014A PH23357A PH 23357 A PH23357 A PH 23357A PH 32014 A PH32014 A PH 32014A PH 32014 A PH32014 A PH 32014A PH 23357 A PH23357 A PH 23357A
Authority
PH
Philippines
Prior art keywords
compound
pharmaceutical composition
composition containing
cyclosporin
cyclosporin compound
Prior art date
Application number
PH32014A
Other languages
English (en)
Inventor
Roland Wenger
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848407618A external-priority patent/GB8407618D0/en
Priority claimed from GB848411922A external-priority patent/GB8411922D0/en
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of PH23357A publication Critical patent/PH23357A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/19—Antibiotic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Transplantation (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PH32014A 1984-03-23 1985-03-20 Cyclosporin compound,pharmaceutical composition containing said compound and method of use thereof PH23357A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848407618A GB8407618D0 (en) 1984-03-23 1984-03-23 Organic compounds
GB848411922A GB8411922D0 (en) 1984-05-10 1984-05-10 Organic compounds

Publications (1)

Publication Number Publication Date
PH23357A true PH23357A (en) 1989-07-14

Family

ID=26287502

Family Applications (2)

Application Number Title Priority Date Filing Date
PH32014A PH23357A (en) 1984-03-23 1985-03-20 Cyclosporin compound,pharmaceutical composition containing said compound and method of use thereof
PH32013A PH21868A (en) 1984-03-23 1985-03-20 Novel cyclosporins

Family Applications After (1)

Application Number Title Priority Date Filing Date
PH32013A PH21868A (en) 1984-03-23 1985-03-20 Novel cyclosporins

Country Status (24)

Country Link
US (1) US4639434A (en])
JP (1) JPH08838B2 (en])
AT (1) AT388737B (en])
BE (1) BE901980A (en])
CA (1) CA1247546A (en])
CH (1) CH667274A5 (en])
CS (1) CS249542B2 (en])
DE (1) DE3509809A1 (en])
DK (1) DK128285A (en])
ES (1) ES8702926A1 (en])
FI (1) FI851120L (en])
FR (1) FR2561651B1 (en])
GB (1) GB2155936B (en])
GR (1) GR850716B (en])
HU (1) HU200786B (en])
IL (1) IL74681A (en])
IT (1) IT1199962B (en])
LU (1) LU85819A1 (en])
NL (1) NL8500828A (en])
NO (1) NO851160L (en])
NZ (1) NZ211526A (en])
PH (2) PH23357A (en])
PT (1) PT80149B (en])
SE (1) SE461334B (en])

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0314862A1 (en) 1984-10-04 1989-05-10 Sandoz Ag Immunogenic conjugates comprising cyclosporins
US4798823A (en) * 1987-06-03 1989-01-17 Merck & Co., Inc. New cyclosporin analogs with modified "C-9 amino acids"
ES2059558T3 (es) * 1987-06-17 1994-11-16 Sandoz Ag Ciclosporins y su uso como productos farmaceuticos.
DE3888357T2 (de) * 1987-06-22 1994-09-15 Merck & Co Inc Cyclosporin-Derivate, die eine modifizierte Aminosäure auf Stellung 8 tragen.
US5227467A (en) * 1987-08-03 1993-07-13 Merck & Co., Inc. Immunosuppressive fluorinated cyclosporin analogs
DE3851152T2 (de) * 1987-09-03 1995-01-26 Univ Georgia Cyclosporin-augenmittel.
US4839342A (en) * 1987-09-03 1989-06-13 University Of Georgia Research Foundation, Inc. Method of increasing tear production by topical administration of cyclosporin
US5089390A (en) * 1987-09-04 1992-02-18 Syntex (U.S.A.) Inc. 2-methyl-4-hexene- and 2-methyl-4-heptene-1,2-diol derivatives
US4914188A (en) * 1987-11-16 1990-04-03 Merck & Co., Inc. Novel 6-position cyclosporin analogs as non-immunosuppressive antagonists of cyclosporin binding to cyclophilin
US5236899A (en) * 1987-11-16 1993-08-17 Merck & Co., Inc. 6-position cyclosporin a analogs as modifiers of cytotoxic drug resistance
CH679119A5 (en]) * 1988-05-13 1991-12-31 Sandoz Ag
US4996193A (en) * 1989-03-03 1991-02-26 The Regents Of The University Of California Combined topical and systemic method of administration of cyclosporine
US5540931A (en) * 1989-03-03 1996-07-30 Charles W. Hewitt Methods for inducing site-specific immunosuppression and compositions of site specific immunosuppressants
GB8916901D0 (en) 1989-07-24 1989-09-06 Sandoz Ltd Improvements in or relating to organic compounds
US5122511A (en) * 1990-02-27 1992-06-16 Merck & Co., Inc. Immunosuppressive cyclosporin analogs with modified amino acids at position-8
US5202310A (en) * 1990-06-06 1993-04-13 Levy Gary A Cyclosporine metabolites
FI111730B (fi) * 1990-11-02 2003-09-15 Novartis Ag Menetelmä ei-immunosuppressiivisen syklosporiinin valmistamiseksi
ES2181734T3 (es) 1990-11-20 2003-03-01 Dade Behring Marburg Gmbh Ensayo inmunologico de ciclosporina.
US5747330A (en) * 1996-06-05 1998-05-05 Poli Industria Chimica Antibiotic producing microbe
RU2170741C2 (ru) * 1996-08-16 2001-07-20 Новартис Аг Способ получения циклоспорина
US20030220234A1 (en) * 1998-11-02 2003-11-27 Selvaraj Naicker Deuterated cyclosporine analogs and their use as immunodulating agents
BR9811716A (pt) 1997-10-08 2000-07-18 Isotechnika Inc Análogos de ciclosporina deuterados e o seu emprego como agentes de modulação imunológica
US5990274A (en) * 1997-11-25 1999-11-23 Dade Behring Inc. Cyclosporine derivatives and uses thereof
US7449544B2 (en) * 1999-11-30 2008-11-11 Cyclacel Limited p21 peptides
RU2321593C9 (ru) 2001-10-19 2008-06-20 Изотехника Инк. Синтез аналогов циклоспорина
WO2003032949A1 (en) * 2001-10-19 2003-04-24 Isotechnika Inc. Novel cyclosporin analog microemulsion preconcentrates
CA2518265A1 (en) * 2003-03-17 2004-09-30 Albany Molecular Research, Inc. Novel cyclosporins
WO2006039164A2 (en) * 2004-09-29 2006-04-13 Amr Technology, Inc. Novel cyclosporin analogues and their pharmaceutical uses
EP1809656A4 (en) * 2004-09-29 2009-03-25 Amr Technology Inc CYCLOSPORINAL KINANALOGA AND ITS PHARMACEUTICAL APPLICATIONS
EP1812037A4 (en) * 2004-10-06 2009-11-11 Amr Technology Inc ALKYNES OF CYCLOSPORINE AND THEIR USEFUL AS PHARMACEUTICAL AGENTS
US7696165B2 (en) * 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders
US7696166B2 (en) * 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders
US7576057B2 (en) 2006-11-20 2009-08-18 Scynexis, Inc. Cyclic peptides
RU2630690C9 (ru) 2010-12-15 2017-12-28 КонтраВир Фармасьютикалз, Инк. МОЛЕКУЛЫ АНАЛОГОВ ЦИКЛОСПОРИНА, МОДИФИЦИРОВАННЫЕ ПО 1 и 3 АМИНОКИСЛОТЕ
HUE044591T2 (hu) 2011-03-11 2019-11-28 Beth Israel Deaconess Medical Ct Inc Anti-CD40 antitestek és alkalmazásuk
CN104877013B (zh) * 2015-06-03 2018-04-20 兰州大学 环孢菌素t及其制备方法和应用
PT3307322T (pt) 2015-09-04 2021-04-23 Primatope Therapeutics Inc Anticorpos anti-cp40 humanizados e as suas utilizações referência cruzada relativa às aplicações associadas

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57140753A (en) * 1981-01-09 1982-08-31 Sandoz Ag Novel cyclosporine
EP0056782B1 (en) * 1981-01-09 1984-08-01 Sandoz Ag Novel cyclosporins

Also Published As

Publication number Publication date
DK128285A (da) 1985-09-24
NL8500828A (nl) 1985-10-16
FI851120A7 (fi) 1985-09-24
GB8507270D0 (en) 1985-04-24
ATA86385A (de) 1989-01-15
CA1247546A (en) 1988-12-28
NZ211526A (en) 1988-08-30
NO851160L (no) 1985-09-24
IL74681A0 (en) 1985-06-30
SE8501392L (sv) 1985-09-24
FR2561651A1 (fr) 1985-09-27
GR850716B (en]) 1985-07-19
BE901980A (fr) 1985-09-23
PT80149B (en) 1987-03-23
DE3509809A1 (de) 1986-01-09
US4639434A (en) 1987-01-27
JPH08838B2 (ja) 1996-01-10
AT388737B (de) 1989-08-25
GB2155936A (en) 1985-10-02
FI851120L (fi) 1985-09-24
IT8547852A1 (it) 1986-09-22
FI851120A0 (fi) 1985-03-20
JPS60215700A (ja) 1985-10-29
PT80149A (en) 1985-04-01
LU85819A1 (fr) 1985-12-12
FR2561651B1 (fr) 1990-03-09
IT1199962B (it) 1989-01-05
CH667274A5 (de) 1988-09-30
CS249542B2 (en) 1987-03-12
IT8547852A0 (it) 1985-03-22
SE461334B (sv) 1990-02-05
GB2155936B (en) 1987-09-16
IL74681A (en) 1989-09-10
SE8501392D0 (sv) 1985-03-21
DK128285D0 (da) 1985-03-21
ES8702926A1 (es) 1987-01-16
HUT38370A (en) 1986-05-28
PH21868A (en) 1988-03-25
HU200786B (en) 1990-08-28
ES541465A0 (es) 1987-01-16

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